Mu-conotoxin CnIlIC, eo hape e tsejoang e le conotoxin CnIlIC, ke peptide ea tlhaho e teng mahlokong a likhofu tsa marine cone conus consor.Peptide ena e fumane tlhokomelo e ngata ho theosa le lilemo bakeng sa ts'ebeliso ea eona e ka bang teng ho litlolo.Mu-conotoxin CnIlIC e ithutoe ka litlamorao tsa eona tse kholo letlalong, 'me bokhoni ba eona ho litlolo tsa litlolo bo ntse bo hlahlojoa bakeng sa bokhoni ba eona ba ho ntlafatsa.
ponahalo ya letlalo le ho thibela ho tsofala.
Tšebeliso ea Mu-conotoxin CnIlIC ho litlolo e tsepamisitse maikutlo ho matla a eona a ho fokotsa ponahalo ea mela e metle le makukuno, ho ntlafatsa letlalo la letlalo, le ho khothalletsa letlalo la bocha le le khanyang haholoanyane.Peptide ena e sebetsa ka ho lebisa li-receptor tse itseng letlalong, e qetellang e etsa hore mesifa ea sefahleho e phomole le ho fokotsa ho honyela ha mesifa ho lebisang ho thehoeng ha mats'oenyeho.
E 'ngoe ea melemo e meholo ea Mu-conotoxin CnIlIC ke bokhoni ba eona ba ho sebetsa e le ntho e khathollang mesifa ha e sebelisoa ka holimo.Ka ho thibela ho lokolloa ha acetylcholine mateanong a neuromuscular, peptide ena ka katleho e fokotsa ho sisinyeha ha mesifa e ipheta-phetang e bakang masoebe a matla joalo ka maoto a lekhoaba, mela e sosobaneng, le masoebe a phatleng.Ka hona, tšebeliso ea kamehla ea Mu-conotoxin CnIlIC mefuteng ea litlolo e ka fella ka letlalo le boreleli, le shebahalang le le le le lenyane.
Ho feta moo, Mu-conotoxin CnIlIC e bontšitsoe ho susumetsa tlhahiso ea collagen le elastin letlalong.Liprotheine tsena li bohlokoa bakeng sa ho boloka letlalo le tsitsitseng le ho tiea, 'me ho fokotseha ha bona ke ntho e tloaelehileng ea ho tsofala.Ka ho khothaletsa collagen le elastin synthesis, Mu-Conotoxin CnIlIC e thusa ho ntlafatsa 'mala oa letlalo, ho fokotsa ho sisinyeha, le ho ntlafatsa sebopeho sa letlalo ka kakaretso bakeng sa chebahalo ea bocha, e boreleli.
Ntle le thepa ea eona e thibelang botsofali, Mu-conotoxin CnIlIC e boetse e na le monyetla oa ho rarolla mathata a mang a letlalo, joalo ka hyperpigmentation le letlalo le sa lekanang.Liphuputso li bontša hore peptide ena e laola tlhahiso le kabo ea melanin, e leng se etsang hore letlalo le be le letlalo le benyang.Ka ho laola mebala le ho fokotsa ho thehoa ha matheba a lefifi, Mu-Conotoxin CnIlIC e thusa ho theha 'mala o hlakileng, o khanyang haholoanyane.
Tšebeliso ea Mu-conotoxin CnIlIC ho litlolo e bula tsela bakeng sa nts'etsopele ea lihlahisoa tse ncha tsa tlhokomelo ea letlalo, tse fanang ka litharollo tse tsoetseng pele bakeng sa liphetoho tsa letlalo tse amanang le lilemo.Ho tloha ho li-serum le litlolo ho isa ho limaske le liphekolo, litlolo tsa litlolo tse nang le peptide ena li etselitsoe ho shebana le matšoao a mangata a botsofali le ho fana ka melemo e felletseng ea tlhokomelo ea letlalo.
Ka ho hlakileng, tšebeliso ea Mu-conotoxin CnIlIC ho litlolo e tšehetsoa ke liteko tse matla le tlhahlobo ea polokeho ho netefatsa hore e sebetsa hantle le hore e mamellehe.Likhamphani tsa litlolo le litsebi tsa tlhokomelo ea letlalo li ntse li tsoela pele ho etsa lipatlisiso le liteko tsa bongaka ho tsoela pele ho lekola bokhoni ba peptide ena le ho ntlafatsa ts'ebeliso ea eona mekhoeng ea tlhokomelo ea letlalo.
Ka kakaretso, Mu-conotoxin CnIlIC e na le litebello tse pharaletseng lefapheng la litlolo, e fana ka mokhoa o mocha oa ho sebetsana le botsofali ba letlalo le ho ntlafatsa boleng ba letlalo ka kakaretso.Ha lipatlisiso le nts'etsopele lefapheng lena li ntse li tsoela pele, ho lebeletsoe hore lihlahisoa tse ngata tsa tlhokomelo ea letlalo tse nang le Mu-conotoxin CnIlIC li tla hlaha ka lebaka la liphello tsa tsona tse kholo tsa kopo.Ka bokhoni ba eona ba ho fokotsa wrinkles, ho ntlafatsa letlalo la letlalo le ho khothalletsa letlalo le khanyang haholoanyane, Mu-Conotoxin CnIlIC e tšepisa ho fetola tsela eo re atamelang tlhokomelo ea letlalo le khahlanong le botsofali le ho phahamisa mekhoa ea litlolo tsa litlolo lilemong tse tlang.
Nako ea poso: Dec-22-2023